Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KRAS | P01116 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31059037 | 0.83 | ABCG2 (0.69) | ABCB1MAPTLMNATNFRSF1AABCG2 | |
| SCHEMBL6779194 | 0.79 | TNFRSF1A (0.77) | ABCB1MAPTLMNAHPGDTNFRSF1A | |
| SCHEMBL6779204 | 0.79 | TNFRSF1A (0.77) | ABCB1MAPTLMNAHPGDTNFRSF1A | |
| SCHEMBL4773932 | 0.78 | MAOB (0.74) | MAPTLMNAHPGDTNFRSF1ASMN1; SMN2 | |
| SCHEMBL27846176 | 0.76 | MAPT (0.73) | MAPTLMNAHPGDTNFRSF1ASMN1; SMN2 | |
| SCHEMBL27846178 | 0.76 | MAPT (0.73) | MAPTLMNAHPGDTNFRSF1ASMN1; SMN2 | |
| SCHEMBL31059019 | 0.74 | TUBB1 (0.80) | ABCB1TNFRSF1AABCG2 | |
| SCHEMBL24253122 | 0.73 | MAPT (0.58) | ABCB1MAPTLMNAHPGDTNFRSF1A | |
| SCHEMBL27173982 | 0.71 | THRB (0.56) | MAPTLMNAHPGDTNFRSF1ASMN1; SMN2 | |
| SCHEMBL1225612 | 0.71 | MAOB (0.71) | MAPTLMNAHPGDTNFRSF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388357-A | Heteroatom-containing chalcone derivative and preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2024-07-26 | — | — | CN | disclosed |