Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | ECE1 | P42892 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105955 | 1.00 | ENPEP (0.35) | ENPEPMMEECE1KDM4EMAPT | |
| SCHEMBL3098199 | 0.85 | ENPEP (0.33) | ENPEPMMEECE1 | |
| SCHEMBL3098192 | 0.85 | ENPEP (0.33) | ENPEPMMEECE1 | |
| SCHEMBL3091754 | 0.82 | MME (0.36) | MMEECE1CA12CA1CA9 | |
| SCHEMBL3091760 | 0.82 | MME (0.36) | MMEECE1CA12CA1CA9 | |
| SCHEMBL2988686 | 0.82 | KDM4E (0.45) | ENPEPMMEECE1KDM4EMAPT | |
| SCHEMBL2988687 | 0.82 | KDM4E (0.45) | ENPEPMMEECE1KDM4EMAPT | |
| SCHEMBL4341296 | 0.80 | LAP3 (0.40) | MMEECE1CA12CA1CA9 | |
| SCHEMBL2976817 | 0.80 | ECE1 (0.36) | MMEECE1CA1MEN1KMT2A | |
| SCHEMBL3105884 | 0.80 | ECE1 (0.36) | MMEECE1CA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |