SCHEMBL31060078

SCHEMBL31060078

Cc1cc(Cl)cc2c(=O)oc(-c3cc(Br)nn3-c3ncccn3)nc12

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PDE4A P27815 1/20 0.31
▸ DHODH Q02127 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29598524 0.87 DHODH (0.43) DHODH
SCHEMBL465839 0.87 DHODH (0.43) DHODH
SCHEMBL29215063 0.87 DHODH (0.36) DHODH
SCHEMBL4163531 0.84 ALDH1A1 (0.34) —
SCHEMBL28531289 0.83 DHODH (0.41) DHODH
SCHEMBL4976959 0.83 DHODH (0.33) DHODH
SCHEMBL15984460 0.83 DHODH (0.33) DHODH
SCHEMBL29791544 0.83 DHODH (0.33) DHODH
SCHEMBL28339194 0.83 DHODH (0.37) DHODH
SCHEMBL15984456 0.81 APEX1 (0.30) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 PDE4A 1594/4885DHODH 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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