SCHEMBL4163531

SCHEMBL4163531

Cc1cc(Cl)cc2c(=O)oc(-c3cc(Br)nn3-c3ccccc3Cl)nc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.34
▸ MAPT P10636 2/20 0.34
▸ NPSR1 Q6W5P4 2/20 0.34
▸ POLB P06746 1/20 0.34
▸ MAPK14 Q16539 2/20 0.33
▸ MAPK11 Q15759 1/20 0.33
▸ C1R P00736 2/20 0.33
▸ OPRM1 P35372 1/20 0.33
▸ MDM4 O15151 1/20 0.33
▸ MDM2 Q00987 1/20 0.33
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ ELANE P08246 1/20 0.32
▸ GSK3B P49841 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ CYP2D6 P10635 2/20 0.32
▸ APEX1 P27695 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5503889 0.91 C1R (0.37) ALDH1A1MAPTNPSR1POLBC1R
SCHEMBL5507360 0.88 CETP (0.35) ALDH1A1MAPK14MAPK11C1RMDM4
SCHEMBL29598524 0.85 DHODH (0.43) ALDH1A1MAPTNPSR1POLBELANE
SCHEMBL465839 0.85 DHODH (0.43) ALDH1A1MAPTNPSR1POLBELANE
SCHEMBL951821 0.85 RXRA (0.46) ELANECNR1
SCHEMBL31060078 0.84 PDE4A (0.31) —
SCHEMBL4975983 0.83 DHODH (0.31) —
SCHEMBL4975775 0.83 ALDH1A1 (0.33) ALDH1A1MAPTNPSR1POLB
SCHEMBL14495052 0.82 ALDH1A1 (0.34) ALDH1A1MAPTNPSR1POLBC1R
SCHEMBL28531289 0.82 DHODH (0.41) ALDH1A1MAPTNPSR1POLBCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2564706-A1 Anthranilamide insecticides E. I. du Pont de Nemours and Company (US) 2013-03-06 — — EP disclosed
US-20090133318-A1 Anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY 2009-05-28 — — US disclosed
EP-1812421-A2 ANTHRANILAMIDE INSECTICIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-08-01 — — EP disclosed
WO-2006055922-A2 ANTHRANILAMIDE INSECTICIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-05-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090133318-A1 Anthranilamide insecticides C3AR1, C5, C1S ALDH1A1 937/4885MAPT 4867/4885NPSR1 1045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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