SCHEMBL961226

SCHEMBL961226

Cc1cc(C#N)cc(C(N)=O)c1NC(=O)c1cc(Cl)nn1-c1ncccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 6/20 0.38
SLC2A3 P11169 6/20 0.38
SLC2A4 P14672 6/20 0.38
SLC2A2 P11168 3/20 0.38
KMT2A Q03164 1/20 0.36
PKM P14618 1/20 0.36
DHODH Q02127 1/20 0.35
MALT1 Q9UDY8 1/20 0.35
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NTRK1 P04629 1/20 0.34
GCK P35557 2/20 0.33
KCNH2 Q12809 2/20 0.33
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31060063 1.00 SLC2A1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL31059983 0.91 DHODH (0.42) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL959387 0.91 DHODH (0.42) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL31060056 0.91 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL13318550 0.91 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL29377007 0.91 DHODH (0.42) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL30845280 0.91 KMT2A (0.36) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL563502 0.91 KMT2A (0.36) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL29215215 0.90 PDE4B (0.38) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A
SCHEMBL15906349 0.89 KMT2A (0.35) SLC2A1SLC2A3SLC2A4SLC2A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247647-B2 Cyano anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-24 US claimed
US-9161540-B2 Cyano anthranilamide insecticides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-10-20 US disclosed
US-8993480-B2 Active ingredient combinations with insecticidal properties BAYER CROPSCIENCE AG (DE) 2015-03-31 US disclosed
US-20130189228-A1 CYANO ANTHRANILAMIDE INSECTICIDES E I DU PONT DE NEMOURS AND COMPANY (US) 2013-07-25 US disclosed
EP-2264022-B1 Cyano anthranilamide insecticides DU PONT (US) 2013-07-24 EP disclosed
US-8475819-B2 Cyano anthranilamide insecticides E I DU PONT DE NEMOURS AND COMPANY (US) 2013-07-02 US disclosed
US-8298989-B2 Active ingredient combinations with insecticidal properties BAYER CROPSCIENCE AG (DE) 2012-10-30 US disclosed
US-20120190544-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2012-07-26 US disclosed
US-20110319452-A1 CYANO ANTHRANILAMIDE INSECTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-12-29 US disclosed
US-7977278-B2 Suspension concentrates BAYER CROPSCIENCE AG (DE) 2011-07-12 US disclosed
US-7875634-B2 contain 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-pyrazole-5-carboxamide; for controlling invertebrate pests in both agronomic and nonagronomic environments E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-01-25 US disclosed
EP-2264022-A1 Cyano anthranilamide insecticides E. I. du Pont de Nemours and Company (US) 2010-12-22 EP disclosed
US-20100099717-A1 SUSPENSION CONCENTRATES FOR IMPROVING THE ROOT ABSORPTION OF AGROCHEMICAL ACTIVE INGREDIENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-04-22 US disclosed
US-20100010051-A1 SUSPENSION CONCENTRATES BAYER CROPSCIENCE AG (DE) 2010-01-14 US disclosed
US-20090306147-A1 BIOLOGICAL EFFICACY OF AGROCHEMICAL COMPOSITIONS ON APPLICATION IN THE GROWTH SUBSTRATE SUITABLE FORMULATIONS AND USE THEREOF BAYER CROPSCIENCE AG (DE) 2009-12-10 US disclosed
US-20090275471-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2009-11-05 US disclosed
US-20070264299-A1 Cyano anthranilamide insecticides FMC CORPORATION 2007-11-15 US disclosed
US-7247647-B2 Cyano anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-24 US disclosed
US-20060111403-A1 Cyano anthranilamide insecticides FMC CORPORATION 2006-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111403-A1 Cyano anthranilamide insecticides C1S, C5, CBR3 SLC2A1 4133/4885SLC2A3 3822/4885SLC2A4 4217/4885
US-20100099717-A1 SUSPENSION CONCENTRATES FOR IMPROVING THE ROOT ABSORPTION OF AGROCHEMICAL ACTIVE INGREDIENTS CROCC, SLC19A1, ABCB11 SLC2A1 45/4885SLC2A3 73/4885SLC2A4 97/4885
US-20110319452-A1 CYANO ANTHRANILAMIDE INSECTICIDES CBR3, C5, C1R SLC2A1 4375/4885SLC2A3 4248/4885SLC2A4 4484/4885
US-20120190544-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES AADAC, ACHE, NAAA SLC2A1 4748/4885SLC2A3 4604/4885SLC2A4 4709/4885
US-20100010051-A1 SUSPENSION CONCENTRATES AKR7A2, CBR3, DCXR SLC2A1 3684/4885SLC2A3 3546/4885SLC2A4 3946/4885
US-20090275471-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES AADAC, ACHE, NAAA SLC2A1 4748/4885SLC2A3 4604/4885SLC2A4 4709/4885
US-20090306147-A1 BIOLOGICAL EFFICACY OF AGROCHEMICAL COMPOSITIONS ON APPLICATION IN THE GROWTH SUBSTRATE SUITABLE FORMULATIONS AND USE THEREOF CYP51A1, CYP21A2, CYP4X1 SLC2A1 4237/4885SLC2A3 3348/4885SLC2A4 4104/4885
US-20130189228-A1 CYANO ANTHRANILAMIDE INSECTICIDES CBR3, C5, C1R SLC2A1 4375/4885SLC2A3 4248/4885SLC2A4 4484/4885
US-20070264299-A1 Cyano anthranilamide insecticides C1S, CBR3, C5 SLC2A1 4310/4885SLC2A3 4290/4885SLC2A4 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.