SCHEMBL3106151

SCHEMBL3106151

O=C(CN(CP(=O)(O)O)CP(=O)(O)O)Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.50
EPHX2 P34913 1/20 0.47
MAPT P10636 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
HTT P42858 1/20 0.45
GAA P10253 3/20 0.44
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
KDM1A O60341 1/20 0.44
SCN1A P35498 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN3A Q9NY46 1/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
HDAC4 P56524 3/20 0.42
HDAC7 Q8WUI4 3/20 0.42
HDAC11 Q96DB2 3/20 0.42
HDAC8 Q9BY41 3/20 0.42
HDAC6 Q9UBN7 3/20 0.42
HDAC9 Q9UKV0 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3108984 0.85 CYP1A1 (0.47) MAPTGAAALDH1A1TSHRCA1
SCHEMBL9639810 0.84 HDAC1 (0.59) HDAC1EPHX2MAPTL3MBTL1HTT
SCHEMBL4365925 0.80 HDAC1 (0.65) HDAC1EPHX2MAPTL3MBTL1HTT
SCHEMBL9974560 0.79 CA1 (0.64) HDAC1EPHX2L3MBTL1TSHRCA1
SCHEMBL8623174 0.77 ALDH1A1 (0.68) HDAC1MAPTL3MBTL1GAAALDH1A1
SCHEMBL13901343 0.77 EPHX2 (0.55) HDAC1EPHX2MAPTL3MBTL1HTT
SCHEMBL5310831 0.76 HDAC1 (0.56) HDAC1EPHX2MAPTL3MBTL1HTT
SCHEMBL27650715 0.76 MEN1 (0.60) HDAC1EPHX2MAPTL3MBTL1HTT
SCHEMBL4272357 0.75 CA1 (0.67) HDAC1TSHRCA1CA2KDM4E
SCHEMBL4268752 0.75 CA1 (0.67) HDAC1TSHRCA1CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100247463-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2010-09-30 US claimed