Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063244 | 0.81 | TUBB1 (0.36) | MAPTHPGDTUBB1TNFRSF1AMMP1 | |
| SCHEMBL31063184 | 0.79 | TUBB1 (0.41) | MAPTHPGDTUBB1TNFRSF1AALOX5 | |
| SCHEMBL31063064 | 0.76 | TUBB1 (0.41) | MAPTHPGDTUBB1TNFRSF1AALOX5 | |
| SCHEMBL31063001 | 0.72 | MAPT (0.33) | MAPTHPGDTUBB1MMP1MMP9 | |
| SCHEMBL31063471 | 0.71 | CYP3A4 (0.51) | HPGDTUBB1TNFRSF1AALOX5STAT3 | |
| SCHEMBL31063149 | 0.69 | ALDH1A1 (0.47) | MAPTHPGDTUBB1TNFRSF1ATUBB4A | |
| SCHEMBL5759025 | 0.69 | ALDH1A1 (0.47) | MAPTHPGDTUBB1TNFRSF1ATUBB4A | |
| SCHEMBL21767678 | 0.69 | LY96 (0.46) | MAPTMMP1MMP9MMP13NFE2L2 | |
| SCHEMBL21767676 | 0.69 | LY96 (0.46) | MAPTMMP1MMP9MMP13NFE2L2 | |
| SCHEMBL1797420 | 0.67 | XDH (0.44) | MAPTHPGDMMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |