Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518690 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1MAPK1KDM4EHPGD | |
| SCHEMBL5608488 | 0.76 | NPSR1 (0.45) | SMN1; SMN2IKBKBNPSR1ALDH1A1MAPK1 | |
| SCHEMBL27822691 | 0.75 | TDP1 (0.52) | SMN1; SMN2IKBKBALDH1A1MAPK1KDM4E | |
| SCHEMBL11806655 | 0.74 | KDM4E (0.46) | ALDH1A1MAPK1KDM4EHPGDHTT | |
| SCHEMBL6110055 | 0.73 | KMT2A (0.39) | SMN1; SMN2IKBKBALDH1A1KDM4ERAB9A | |
| SCHEMBL5364490 | 0.72 | ALDH1A1 (0.38) | SMN1; SMN2KCNJ1IKBKBALDH1A1MAPK1 | |
| SCHEMBL6171824 | 0.72 | NOS3 (0.45) | SMN1; SMN2KCNJ1IKBKBKDM4ERAB9A | |
| SCHEMBL15448563 | 0.71 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1MAPK1KDM4EHTT | |
| SCHEMBL20061334 | 0.71 | TSHR (0.48) | SMN1; SMN2NPSR1ALDH1A1KDM4EHPGD | |
| SCHEMBL30937735 | 0.70 | KCNJ1 (0.46) | SMN1; SMN2KCNJ1ALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111771001-B | Enhanced nucleic acid polymerization by aromatic compounds | F·霍夫曼-罗氏股份公司 | 2024-09-06 | — | — | CN | disclosed |