Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 7/20 | 0.41 |
| ▸ | CDK7 | P50613 | 6/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CCNH | P51946 | 5/20 | 0.37 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31064534 | 0.89 | CDK9 (0.41) | CDK9CDK7CDK4CDK2PIK3CD | |
| SCHEMBL31064105 | 0.87 | CDK2 (0.51) | CDK9CDK7CDK4CDK2CCNH | |
| SCHEMBL31064107 | 0.86 | CDK9 (0.42) | CDK9CDK7CDK4CDK2PIK3CD | |
| SCHEMBL31064465 | 0.76 | CDK2 (0.41) | CDK9CDK7CDK4CDK2 | |
| SCHEMBL23547341 | 0.74 | ALDH1A1 (0.49) | CDK9CDK7CDK4CDK2NPC1 | |
| SCHEMBL31064296 | 0.69 | CDK7 (0.50) | CDK9CDK7CDK4CDK2CCNH | |
| SCHEMBL31064118 | 0.69 | CDK4 (0.51) | CDK9CDK7CDK4PIK3CDNPC1 | |
| SCHEMBL23547346 | 0.69 | CDK9 (0.51) | CDK9CDK7CDK4CDK2NPC1 | |
| SCHEMBL23529883 | 0.68 | CDK9 (0.54) | CDK9CDK7CDK4CDK2PIK3CD | |
| SCHEMBL31064099 | 0.67 | CDK9 (0.49) | CDK9CDK7CDK4CDK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175024-A1 | NEW FUSED HETEROCYCLIC COMPOUND AS CDKS INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2024-08-29 | — | — | WO | disclosed |