Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.41 |
| ▸ | CDK9 | P50750 | 17/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23547341 | 0.79 | ALDH1A1 (0.49) | CDK2CDK9CDK4CDK7CCNA2 | |
| SCHEMBL31064107 | 0.77 | CDK9 (0.42) | CDK2CDK9CDK4CDK7 | |
| SCHEMBL31064134 | 0.76 | KAT2B (0.42) | CDK2CDK9CDK4CDK7 | |
| SCHEMBL31064153 | 0.76 | CDK9 (0.41) | CDK2CDK9CDK4CDK7 | |
| SCHEMBL31064144 | 0.75 | CDK2 (0.43) | CDK2CDK9CDK4CDK7CCNT1 | |
| SCHEMBL16659551 | 0.75 | CDK2 (0.36) | CDK2CDK9CDK7SRCCCNT1 | |
| SCHEMBL1486116 | 0.72 | CSNK2B (0.50) | SRCPDE7AADORA1 | |
| SCHEMBL19912801 | 0.72 | CDK2 (0.41) | CDK2CDK9CDK4CDK7ADORA1 | |
| SCHEMBL23547517 | 0.72 | CDK9 (0.45) | CDK2CDK9CDK4CDK7 | |
| SCHEMBL15241430 | 0.72 | CDK2 (0.40) | CDK2CDK9CDK4CDK7SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175024-A1 | NEW FUSED HETEROCYCLIC COMPOUND AS CDKS INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2024-08-29 | — | — | WO | disclosed |