Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 6/20 | 0.53 |
| ▸ | CDK2 | P24941 | 5/20 | 0.53 |
| ▸ | CDK7 | P50613 | 17/20 | 0.51 |
| ▸ | CDK4 | P11802 | 3/20 | 0.51 |
| ▸ | CCNH | P51946 | 14/20 | 0.51 |
| ▸ | MNAT1 | P51948 | 14/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31064163 | 1.00 | CDK9 (0.53) | CDK9CDK2CDK7CDK4CCNH | |
| SCHEMBL19896545 | 0.94 | CDK2 (0.58) | CDK9CDK2CDK7CDK4CCNH | |
| SCHEMBL23547346 | 0.86 | CDK9 (0.51) | CDK9CDK2CDK7CDK4CCNH | |
| SCHEMBL31063988 | 0.86 | CDK2 (0.52) | CDK9CDK2CDK7CDK4CCNH | |
| SCHEMBL30865954 | 0.85 | CDK2 (0.56) | CDK9CDK2CDK7CDK4CCNH | |
| SCHEMBL23547459 | 0.81 | CDK9 (0.49) | CDK9CDK2CDK7CDK4CCNH | |
| SCHEMBL31064123 | 0.80 | CDK2 (0.48) | CDK9CDK2CDK7CDK4CCNH | |
| SCHEMBL29842296 | 0.80 | CDK2 (0.57) | CDK9CDK2CDK7CDK4CCNH | |
| SCHEMBL23529883 | 0.80 | CDK9 (0.54) | CDK9CDK2CDK7CDK4 | |
| SCHEMBL23547353 | 0.79 | ALDH1A1 (0.51) | CDK9CDK2CDK7CDK4CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175024-A1 | NEW FUSED HETEROCYCLIC COMPOUND AS CDKS INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2024-08-29 | — | — | WO | disclosed |