Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963562 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL22616159 | 0.83 | CFD (0.51) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL7138575 | 0.74 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL54695 | 0.74 | KMT2A (0.54) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL27932230 | 0.73 | TDP1 (0.58) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL10712556 | 0.73 | HPGD (0.50) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL31462928 | 0.72 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL5842967 | 0.72 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL2707336 | 0.71 | TDP1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL11904537 | 0.71 | TDP1 (0.61) | ALDH1A1HPGDKDM4EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270740-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. | 2024-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270740-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | CGAS, GMPS, PRKG1 | ALDH1A1 1281/4885HPGD 598/4885KDM4E 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.