Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.41 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904537 | 0.77 | TDP1 (0.61) | TDP1ALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL38726 | 0.77 | TDP1 (0.61) | TDP1ALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL31064999 | 0.75 | HTT (0.55) | ALDH1A1HPGDPOLBMEN1KMT2A | |
| Bromide SCHEMBL20513084 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1HPGDPOLBMEN1 | |
| Fluoride SCHEMBL21331933 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL23727166 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL18074260 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1HPGDPOLBMEN1 | |
| Fluoride SCHEMBL20513066 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1HPGDPOLBMEN1 | |
| Ammonia Solution, Strong SCHEMBL16240294 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL18074258 | 0.75 | TDP1 (0.58) | TDP1ALDH1A1HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234466-A1 | NEW PROCESS FOR PREPARING 3-HYDROXY-2-PYRONE | POLITECNICO DI MILANO (IT) | 2022-11-10 | — | — | WO | claimed |
| EP-4651944-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| EP-4652164-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| EP-4638446-A1 | THIADIAZOLE DERIVATIVES AS INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| EP-4554928-A1 | ELASTOMER COMPOSITIONS COMPRISING AT LEAST ONE SP2 HYBRIDIZED CARBON ALLOTROPE AND A 2,5-DISUBSTITUTED PYRROLE DERIVATIVE | Pirelli Tyre S.p.A. (IT) | 2025-05-21 | — | — | EP | disclosed |
| US-12258275-B2 | Elastomer compositions comprising an adduct between an SP2 hybridized carbon allotrope and a dicarboxylic acid derivative | PIRELLI TYRE S.P.A. (IT) | 2025-03-25 | — | — | US | disclosed |
| CN-119562943-A | Comprising at least one sp2Elastomeric compositions of hybrid carbon allotrope and 2, 5-disubstituted pyrrole derivatives | 倍耐力轮胎股份公司 | 2025-03-04 | — | — | CN | disclosed |
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
| WO-2024233812-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024233767-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| US-8263629-B2 | Substituted aminobutyric derivatives as neprilysin inhibitors | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | disclosed |
| US-8263629-B2 | Substituted aminobutyric derivatives as neprilysin inhibitors | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | disclosed |
| US-8263629-B2 | Substituted aminobutyric derivatives as neprilysin inhibitors | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | disclosed |
| WO-2012075053-A2 | LIGNIN OXIDATION AND PRODUCTS THEREOF | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| EP-2435402-A2 | SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS | Novartis AG (CH) | 2012-04-04 | — | — | EP | disclosed |
| WO-2010136474-A2 | SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS | NOVARTIS AG (CH) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136474-A2 | SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS | NOVARTIS AG (CH) | 2010-12-02 | — | — | WO | disclosed |
| US-20100305145-A1 | Substituted Aminobutyric Derivatives as Neprilysin Inhibitors | NOVARTIS AG (CH) | 2010-12-02 | — | — | US | disclosed |
| US-20100305145-A1 | Substituted Aminobutyric Derivatives as Neprilysin Inhibitors | NOVARTIS AG (CH) | 2010-12-02 | — | — | US | disclosed |
| US-20100305145-A1 | Substituted Aminobutyric Derivatives as Neprilysin Inhibitors | NOVARTIS AG (CH) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CGAS, TDP1, CYP11B2 | TDP1 2/4885ALDH1A1 987/4885HPGD 516/4885 |
| US-20100305145-A1 | Substituted Aminobutyric Derivatives as Neprilysin Inhibitors | MME, GABRB1, GABRE | TDP1 1584/4885ALDH1A1 1125/4885HPGD 2249/4885 |
| US-12258275-B2 | Elastomer compositions comprising an adduct between an SP2 hybridized carbon allotrope and a dicarboxylic acid derivative | FUT6, FUT5, GNE | TDP1 4178/4885ALDH1A1 448/4885HPGD 842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.