Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 17/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.58 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31064967 | 0.89 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL31064959 | 0.87 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL31064953 | 0.87 | RIPK1 (1.00) | RIPK1MKNK1MKNK2 | |
| SCHEMBL31428565 | 0.75 | RIPK1 (0.60) | RIPK1L3MBTL1KDM4EMKNK1MKNK2 | |
| SCHEMBL31043131 | 0.75 | RIPK1 (0.60) | RIPK1L3MBTL1KDM4EMKNK1MKNK2 | |
| SCHEMBL19145573 | 0.75 | RIPK1 (0.59) | RIPK1L3MBTL1KDM4EMKNK1MKNK2 | |
| SCHEMBL19126755 | 0.73 | RIPK1 (0.57) | RIPK1L3MBTL1KDM4EMKNK1MKNK2 | |
| SCHEMBL8260488 | 0.73 | SIGMAR1 (0.72) | RIPK1L3MBTL1KDM4EMKNK1MKNK2 | |
| SCHEMBL18741322 | 0.72 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL31064952 | 0.72 | RIPK1 (0.67) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344359-A | RIPK1 kinase targeted inhibitor and application thereof | 中国药科大学 | 2024-07-16 | — | — | CN | disclosed |