Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.58 |
| ▸ | PDE4A | P27815 | 5/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326960 | 0.82 | ADORA2A (0.67) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL60158 | 0.79 | ADORA2A (0.70) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30025357 | 0.79 | ADORA2A (0.66) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5515444 | 0.77 | ADORA2A (0.71) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4602969 | 0.75 | ADORA2B (0.73) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27586849 | 0.74 | ADORA2A (0.71) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL380135 | 0.74 | ADORA2A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27396492 | 0.74 | ADORA2A (1.00) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9386893 | 0.73 | ADORA2A (0.70) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7217322 | 0.73 | ADORA2A (0.97) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4602044-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | invIOs GmbH (AT) | 2025-08-20 | — | — | EP | disclosed |
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |