Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20594412 | 1.00 | CES2 (0.40) | CES2CES1POLBMCOLN3ABL1 | |
| SCHEMBL8729538 | 0.87 | CES2 (0.44) | CES2CES1POLBMCOLN3ABL1 | |
| SCHEMBL7572960 | 0.84 | ABL1 (0.41) | POLBMCOLN3ABL1CA12CA1 | |
| SCHEMBL19612048 | 0.82 | ABL1 (0.38) | CES2CES1POLBMCOLN3ABL1 | |
| SCHEMBL30993252 | 0.82 | ABL1 (0.38) | CES2CES1POLBMCOLN3ABL1 | |
| SCHEMBL24718703 | 0.81 | ABL1 (0.44) | POLBMCOLN3ABL1CA12CA1 | |
| SCHEMBL30798415 | 0.81 | ABL1 (0.44) | POLBMCOLN3ABL1CA12CA1 | |
| SCHEMBL5557509 | 0.80 | LMNA (0.44) | POLBMCOLN3ALDH1A1LMNASLC6A4 | |
| SCHEMBL382348 | 0.80 | CES2 (0.61) | CES2CES1POLBABL1CA12 | |
| SCHEMBL489805 | 0.79 | ALDH1A1 (0.42) | CES2CES1POLBABL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132972-B | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2024-07-12 | — | — | CN | disclosed |