SCHEMBL31065779

SCHEMBL31065779

Cc1nc(C2CC2c2ccc(C(=O)NC3CC4CCC(C=O)(C3)N4C(=O)O)cc2Cl)c2ccsc2n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PTK2 Q05397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31065787 0.90 MEN1 (0.35) MEN1KMT2APTK2
SCHEMBL31065799 0.88 MEN1 (0.32) MEN1KMT2APTK2
SCHEMBL31065778 0.88 MEN1 (0.32) MEN1KMT2APTK2
SCHEMBL31065788 0.86 PTK2 (0.33) MEN1KMT2APTK2
SCHEMBL31065807 0.82 CSNK2A1 (0.34) MEN1KMT2APTK2
SCHEMBL31065793 0.77 CSNK2A1 (0.35)
SCHEMBL31065781 0.75 MEN1 (0.34) MEN1KMT2A
SCHEMBL31065790 0.75 PLD3 (0.30)
SCHEMBL31065752 0.74 GPR119 (0.35) PTK2
SCHEMBL31065769 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024131942-A1 CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海深势唯思科技有限责任公司 2024-06-27 WO disclosed