Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065779 | 0.90 | MEN1 (0.32) | MEN1KMT2APTK2 | |
| SCHEMBL31065778 | 0.90 | MEN1 (0.32) | MEN1KMT2APTK2PAK4OPRK1 | |
| SCHEMBL31065799 | 0.90 | MEN1 (0.32) | MEN1KMT2APTK2OPRK1 | |
| SCHEMBL31065788 | 0.88 | PTK2 (0.33) | MEN1KMT2APTK2 | |
| SCHEMBL31065807 | 0.84 | CSNK2A1 (0.34) | MEN1KMT2APTK2CSNK2A1BRD4 | |
| SCHEMBL31065781 | 0.81 | MEN1 (0.34) | MEN1KMT2AEZH2 | |
| SCHEMBL31065793 | 0.78 | CSNK2A1 (0.35) | CSNK2A1 | |
| SCHEMBL31065790 | 0.77 | PLD3 (0.30) | — | |
| SCHEMBL31065752 | 0.76 | GPR119 (0.35) | PTK2 | |
| SCHEMBL31065769 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |