Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 9/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065763 | 0.83 | USP30 (0.47) | USP30 | |
| SCHEMBL31065776 | 0.82 | GPR119 (0.32) | USP30 | |
| SCHEMBL31065748 | 0.81 | USP30 (0.32) | USP30 | |
| SCHEMBL31065745 | 0.81 | — | — | |
| SCHEMBL31065809 | 0.81 | PLD3 (0.32) | — | |
| SCHEMBL31065750 | 0.81 | GPR119 (0.32) | USP30 | |
| SCHEMBL31065766 | 0.79 | AURKA (0.32) | — | |
| SCHEMBL31065803 | 0.78 | USP30 (0.38) | USP30 | |
| SCHEMBL30968142 | 0.78 | USP30 (0.38) | USP30 | |
| SCHEMBL31065780 | 0.77 | PLD3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131942-A1 | CYCLOPROPANE TLR7 AND TLR8 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-06-27 | — | — | WO | disclosed |