Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | CCR5 | P51681 | 5/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065803 | 1.00 | USP30 (0.38) | USP30GPR119CCR5SUV39H2PTAFR | |
| SCHEMBL31065785 | 0.90 | USP30 (0.39) | USP30GPR119CCR5SUV39H2PTAFR | |
| SCHEMBL30968109 | 0.90 | USP30 (0.39) | USP30GPR119CCR5SUV39H2PTAFR | |
| SCHEMBL31065774 | 0.89 | GPR119 (0.36) | USP30GPR119SUV39H2 | |
| SCHEMBL30968006 | 0.89 | GPR119 (0.36) | USP30GPR119SUV39H2 | |
| SCHEMBL30967959 | 0.83 | CHRM4 (0.36) | USP30CCR5PTAFRCHRM4HRH3 | |
| SCHEMBL30968010 | 0.83 | CHRM4 (0.36) | USP30CCR5PTAFRCHRM4HRH3 | |
| SCHEMBL30968035 | 0.83 | CHRM4 (0.36) | USP30CCR5PTAFRCHRM4HRH3 | |
| SCHEMBL30968100 | 0.82 | PTAFR (0.35) | PTAFRMEN1KMT2ACHRM4HRH3 | |
| SCHEMBL30968042 | 0.82 | PTAFR (0.35) | PTAFRMEN1KMT2ACHRM4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |