Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35212261 | 0.80 | FLT3 (0.38) | NPC1RAB9AKDM5BFLT3FGFR1 | |
| SCHEMBL22774288 | 0.77 | KDM5B (0.40) | NPC1RAB9AKDM5BFLT3FGFR1 | |
| SCHEMBL878011 | 0.77 | KDM5B (0.38) | NPC1RAB9AKDM5BFLT3FGFR1 | |
| SCHEMBL13035401 | 0.77 | GABRA1 (0.39) | NPC1RAB9AMEN1KMT2AKDM5B | |
| SCHEMBL31510377 | 0.77 | KDM5B (0.40) | NPC1RAB9AMEN1KMT2AKDM5B | |
| SCHEMBL29525193 | 0.77 | KDM5B (0.40) | NPC1RAB9AKDM5BFLT3FGFR1 | |
| SCHEMBL15286385 | 0.76 | KDM5B (0.39) | KDM5BFLT3FGFR1FGFR2FGFR4 | |
| SCHEMBL31180433 | 0.74 | KDM5B (0.36) | KDM5BFLT3FGFR1FGFR2FGFR4 | |
| SCHEMBL15760929 | 0.74 | RXRA (0.38) | NPC1RAB9AKDM5BFLT3FGFR1 | |
| SCHEMBL18485075 | 0.73 | KDM5B (0.39) | KDM5BFLT3FGFR1FGFR2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673139-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182742-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |