Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31065882 | 0.73 | ERN1 (0.39) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL27166994 | 0.72 | NPC1 (0.42) | — | |
| SCHEMBL2947290 | 0.71 | ERN1 (0.39) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL1619349 | 0.69 | ERN1 (0.44) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL4976027 | 0.68 | CES1 (0.44) | CA1 | |
| SCHEMBL29262005 | 0.68 | MEN1 (0.36) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL31166817 | 0.68 | RXFP1 (0.44) | ERN1 | |
| SCHEMBL17858390 | 0.67 | ERN1 (0.40) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL25972038 | 0.66 | MTNR1A (0.49) | GPR119 | |
| SCHEMBL2139973 | 0.66 | ERN1 (0.46) | ERN1TLR2TLR1TLR6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673139-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182742-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |