Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31066388 | 0.87 | PDE3B (0.42) | GAAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL31066340 | 0.85 | CYP1A2 (0.40) | LMNATSHRHTTTGFBR1NPC1 | |
| SCHEMBL31066452 | 0.84 | NPC1 (0.40) | LMNAGAATSHRHTTNPC1 | |
| SCHEMBL31066475 | 0.84 | GAA (0.41) | LMNAGAATSHRHTTNPC1 | |
| SCHEMBL31066470 | 0.81 | LMNA (0.40) | LMNAGAATSHRHTTNPC1 | |
| SCHEMBL31066286 | 0.81 | GAA (0.40) | LMNAGAATSHRHTTNPC1 | |
| SCHEMBL31066381 | 0.80 | GAA (0.42) | LMNAGAATSHRHTTNPC1 | |
| SCHEMBL31066524 | 0.80 | GAA (0.40) | LMNAGAATSHRHTTNPC1 | |
| SCHEMBL23414986 | 0.72 | ALDH1A1 (0.48) | LMNAGAATSHRHTTTHRB | |
| SCHEMBL31066451 | 0.72 | ALDH1A1 (0.39) | LMNATSHRHTTTHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182447-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |