Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31066375 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPK1NPSR1MAPTKMT2A | |
| SCHEMBL23414986 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPK1NPSR1TP53MAPT | |
| SCHEMBL29852457 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPK1TP53MAPTTHRB | |
| SCHEMBL31158416 | 0.77 | MAPK1 (0.42) | ALDH1A1MAPK1NPSR1TP53MAPT | |
| SCHEMBL23961101 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPK1NPSR1TP53MAPT | |
| SCHEMBL31066448 | 0.75 | OPRM1 (0.34) | NPSR1 | |
| SCHEMBL31066442 | 0.74 | DRD3 (0.34) | NPSR1 | |
| SCHEMBL31158519 | 0.74 | MAPK1 (0.39) | ALDH1A1MAPK1NPSR1KMT2AHPGD | |
| SCHEMBL31714739 | 0.73 | ALDH1A1 (0.45) | ALDH1A1MAPK1NPSR1MAPTKMT2A | |
| SCHEMBL31066499 | 0.72 | LMNA (0.43) | ALDH1A1NPSR1TP53MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182447-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |