Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1E | P28566 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66920 | 0.87 | LMNA (0.54) | HTR1ES1PR3MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11359974 | 0.85 | LMNA (0.53) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL6218234 | 0.85 | HTR1E (0.46) | HTR1ES1PR3LMNAALDH1A1CYP2C19 | |
| SCHEMBL6218048 | 0.85 | HTR1E (0.46) | HTR1ES1PR3LMNAALDH1A1CYP2C19 | |
| SCHEMBL31066507 | 0.85 | BCL2A1 (0.51) | ALDH1A1 | |
| SCHEMBL28622389 | 0.83 | HTR1E (0.65) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL69127 | 0.83 | HTR1E (0.65) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL67619 | 0.83 | HTR1E (0.60) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL12531975 | 0.81 | HTR1E (0.63) | HTR1ES1PR3MEN1KMT2ALMNA | |
| SCHEMBL17844351 | 0.81 | CYP2D6 (0.43) | HTR1ES1PR3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182447-A1 | COMPOUNDS AND METHODS FOR MODULATING RAS-PI3K | VIVIDION THERAPEUTICS, INC. (US) | 2024-09-06 | — | — | WO | disclosed |