Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29757597 | 0.82 | MEN1 (0.42) | NAMPTKMT2AIDH1 | |
| SCHEMBL31569180 | 0.82 | MEN1 (0.42) | NAMPTKMT2AIDH1 | |
| SCHEMBL15355395 | 0.78 | OPRM1 (0.49) | NPC1ALDH1A1NOTUM | |
| SCHEMBL15222062 | 0.76 | DPP8 (0.38) | DPP8DPP9NAMPT | |
| SCHEMBL23326979 | 0.75 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL25429344 | 0.74 | ABHD6 (0.41) | ALDH1A1 | |
| SCHEMBL25428241 | 0.74 | OPRM1 (0.31) | — | |
| SCHEMBL25428247 | 0.74 | OPRM1 (0.31) | — | |
| SCHEMBL25431503 | 0.74 | ABHD6 (0.41) | ALDH1A1 | |
| SCHEMBL22438629 | 0.73 | DPP4 (0.35) | DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728976-B | Hydrogen-1H-pyrrolo [1,2-a ] pyrazine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2024-08-16 | — | — | CN | disclosed |