SCHEMBL31067149

SCHEMBL31067149

Fc1ccc(-c2ccccc2F)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.51
GRM2 Q14416 2/20 0.43
GPR3 P46089 1/20 0.42
PTPN1 P18031 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
NISCH Q9Y2I1 1/20 0.42
HTR1A P08908 1/20 0.41
HTR7 P34969 1/20 0.41
PDE3B Q13370 1/20 0.40
PDE3A Q14432 1/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
CASP6 P55212 1/20 0.40
KMT2A Q03164 1/20 0.40
PTPRC P08575 1/20 0.39
FABP4 P15090 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31067122 0.83 HSD11B1 (0.44) HSD11B1GPR3PTPN1L3MBTL1CASP3
SCHEMBL11637227 0.83 HSD11B1 (0.61) HSD11B1GPR3
SCHEMBL20989248 0.82 NFE2L2 (0.48) GPR3PTPN1L3MBTL1CASP3SENP8
SCHEMBL321960 0.80 ESR1 (0.53) HSD11B1
SCHEMBL16013589 0.80 PLA2G7 (0.49) HSD11B1MEN1GAAKMT2APTPRC
SCHEMBL17268322 0.80 HSD11B1 (0.50) HSD11B1GRM2PTPN1L3MBTL1CASP3
SCHEMBL19033931 0.80 HSD11B1 (0.43) HSD11B1PTPN1MEN1KMT2APTPRC
SCHEMBL8974385 0.80 CYP2A6 (0.50) HSD11B1MEN1KMT2APTPRC
SCHEMBL30543346 0.79 PTPN1 (0.50) HSD11B1GPR3PTPN1L3MBTL1CASP3
SCHEMBL23282799 0.79 HSD11B1 (0.47) HSD11B1GRM2GPR3NISCHHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3694849-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2024-07-31 EP disclosed