SCHEMBL31067152

SCHEMBL31067152

Fc1ccc(-c2ccccc2F)cc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.58
PTGS1 P23219 2/20 0.58
PTPRC P08575 1/20 0.52
PTPN1 P18031 1/20 0.52
ACMSD Q8TDX5 1/20 0.46
BACE1 P56817 1/20 0.45
TRPA1 O75762 1/20 0.45
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
PDK2 Q15119 1/20 0.44
DHODH Q02127 1/20 0.43
MAP4K4 O95819 1/20 0.42
NISCH Q9Y2I1 1/20 0.42
PLA2G1B P04054 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20898128 1.00 PTGS2 (0.58) PTGS2PTGS1PTPRCPTPN1ACMSD
SCHEMBL31067169 0.83 PTPRC (0.52) PTGS2PTGS1PTPRCPTPN1ACMSD
SCHEMBL13615027 0.83 PTPRC (0.52) PTGS2PTGS1PTPRCPTPN1ACMSD
SCHEMBL3755924 0.82 PTGS2 (0.54) PTGS2PTGS1ADORA2AADORA1NISCH
SCHEMBL31161110 0.82 PTGS2 (0.58) PTGS2PTGS1ADORA2AADORA1CYP3A4
SCHEMBL397260 0.82 PTGS2 (0.58) PTGS2PTGS1ADORA2AADORA1CYP3A4
SCHEMBL31232639 0.82 PTGS2 (0.58) PTGS2PTGS1ADORA2AADORA1NISCH
SCHEMBL3755926 0.82 PTGS2 (0.58) PTGS2PTGS1PDK2BRD4CREBBP
SCHEMBL2138372 0.80 APEX1 (0.57) PTGS2PTGS1PTPRCPTPN1ACMSD
SCHEMBL13439490 0.80 PTPRC (0.57) PTPRCPTPN1ACMSDBACE1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3694849-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2024-07-31 EP disclosed