Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17073423 | 1.00 | CPN1 (0.41) | CPN1CPB2PNMTCHRM1CHRM3 | |
| SCHEMBL17073486 | 0.83 | RIPK1 (0.39) | CHRM1CHRM3RIPK1 | |
| SCHEMBL30446809 | 0.82 | HRH1 (0.40) | CPN1CPB2 | |
| SCHEMBL25667743 | 0.82 | CPN1 (0.36) | CPN1CPB2CHRM1CHRM3CYP3A4 | |
| SCHEMBL17064662 | 0.82 | HRH1 (0.40) | CPN1CPB2 | |
| SCHEMBL17073447 | 0.80 | RIPK1 (0.53) | GRIN2BRIPK1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL13323806 | 0.77 | CPN1 (0.46) | CPN1CPB2PNMTIDO1CYP3A4 | |
| SCHEMBL28025342 | 0.77 | CPN1 (0.46) | CPN1CPB2PNMTIDO1CYP3A4 | |
| SCHEMBL17064475 | 0.76 | ADRB1 (0.35) | CHRM1CHRM3GRIN2BCYP3A4 | |
| SCHEMBL17064585 | 0.76 | MAPKAPK2 (0.41) | CPN1CPB2IDO1CYP3A4SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |