Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064305 | 1.00 | MAOB (0.71) | MAOBSMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL477599 | 0.91 | SMN1; SMN2 (0.62) | MAOBSMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL17064786 | 0.90 | MAOB (0.60) | MAOBSMN1; SMN2KMT2ALMNAHPGD | |
| 3-(Benzyloxy)Aniline SCHEMBL29428912 | 0.84 | MAOB (1.00) | MAOBSMN1; SMN2APPCYP4F2CYP4A11 | |
| 3-(Benzyloxy)Aniline SCHEMBL291445 | 0.84 | MAOB (1.00) | MAOBSMN1; SMN2APPCYP4F2CYP4A11 | |
| SCHEMBL4707722 | 0.84 | ALOX5 (0.59) | MAOBSMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL7713126 | 0.84 | SMN1; SMN2 (0.56) | MAOBSMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL17064406 | 0.84 | MAOB (0.57) | MAOBSMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL4822571 | 0.83 | MAOB (0.68) | MAOBSMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL5772077 | 0.83 | KMT2A (0.62) | MAOBSMN1; SMN2KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |