Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4101289 | 0.87 | RAB9A (0.36) | MAPTRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL14253653 | 0.87 | RAB9A (0.48) | MAPTRAB9ASMN1; SMN2NPC1THRB | |
| SCHEMBL3117697 | 0.86 | RAB9A (0.35) | MAPTRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL3113314 | 0.84 | GAA (0.43) | MAPTRAB9ASMN1; SMN2NPC1THRB | |
| SCHEMBL3109031 | 0.81 | RAB9A (0.36) | MAPTRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL3121441 | 0.77 | RAB9A (0.35) | MAPTRAB9ASMN1; SMN2NPC1RECQL | |
| SCHEMBL3114583 | 0.77 | IRAK4 (0.42) | — | |
| SCHEMBL12903702 | 0.73 | HTT (0.51) | MAPTRAB9ASMN1; SMN2NPC1RXFP1 | |
| SCHEMBL7786621 | 0.73 | RAB9A (0.40) | MAPTRAB9ASMN1; SMN2NPC1THRB | |
| SCHEMBL2911307 | 0.72 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1RECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575064-B2 | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG (DE) | 2013-11-05 | — | — | US | disclosed |
| US-20130281292-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281496-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130281500-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-24 | — | — | US | disclosed |
| US-20130274100-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130274099-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130274101-A1 | Synergistic Fungicidal Active Substance Combinations | WACHENDORFF-NEUMANN ULRIKE (DE) | 2013-10-17 | — | — | US | disclosed |
| CN-101184391-B | Substance combinations with synergistic fungicidal activity | BAYER CROPSCIENCE AG | 2013-07-24 | — | — | CN | disclosed |
| CN-102907432-A | Synergistic fungicidal active substance combinations | BAYER CROPSCIENCE AG | 2013-02-06 | — | — | CN | disclosed |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | BAYER CROPSCIENCE AG (DE) | 2010-10-28 | — | — | US | disclosed |
| CN-101184391-A | Substance combinations with synergistic fungicidal activity | BAYER CROPSCIENCE AG (DE) | 2008-05-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281496-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | MAPT 4293/4885RAB9A 1572/4885SMN1; SMN2 3004/4885 |
| US-20100273648-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | MAPT 4293/4885RAB9A 1572/4885SMN1; SMN2 3004/4885 |
| US-20130281500-A1 | Synergistic Fungicidal Active Substance Combinations | CAT, CYP1A2, GABBR1 | MAPT 4023/4885RAB9A 1647/4885SMN1; SMN2 3381/4885 |
| US-20130274100-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | MAPT 4293/4885RAB9A 1572/4885SMN1; SMN2 3004/4885 |
| US-20130274099-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | MAPT 4293/4885RAB9A 1572/4885SMN1; SMN2 3004/4885 |
| US-20130274101-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | MAPT 4293/4885RAB9A 1572/4885SMN1; SMN2 3004/4885 |
| US-20130281292-A1 | Synergistic Fungicidal Active Substance Combinations | GLRA1, GRM1, CYP1A2 | MAPT 4293/4885RAB9A 1572/4885SMN1; SMN2 3004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.