Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106873 | 0.87 | MAPT (0.37) | RAB9ASMN1; SMN2NPC1MAPTRECQL | |
| SCHEMBL3117697 | 0.86 | RAB9A (0.35) | RAB9ASMN1; SMN2NPC1MAPTRECQL | |
| SCHEMBL15132717 | 0.85 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1MAPTRECQL | |
| SCHEMBL12798725 | 0.77 | ATM (0.38) | — | |
| SCHEMBL3109031 | 0.77 | RAB9A (0.36) | RAB9ASMN1; SMN2NPC1MAPTRECQL | |
| SCHEMBL3121441 | 0.75 | RAB9A (0.35) | RAB9ASMN1; SMN2NPC1MAPTRECQL | |
| SCHEMBL5577995 | 0.75 | ABCC1 (0.37) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL14253653 | 0.73 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1MAPTRECQL | |
| SCHEMBL12903702 | 0.73 | HTT (0.51) | RAB9ASMN1; SMN2NPC1MAPTRECQL | |
| SCHEMBL2911307 | 0.72 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1RECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101212899-B | Carboxamides | BAYER CROPSCIENCE AG | 2012-11-21 | — | — | CN | claimed |
| US-20090105311-A1 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | claimed |
| EP-1890540-A2 | CARBOXAMIDES | Bayer CropScience AG (DE) | 2008-02-27 | — | — | EP | claimed |
| WO-2006131221-A2 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | claimed |
| US-20130190375-A1 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-07-25 | — | — | US | disclosed |
| US-8431600-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2013-04-30 | — | — | US | disclosed |
| US-8431600-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2013-04-30 | — | — | US | disclosed |
| US-8431600-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2013-04-30 | — | — | US | disclosed |
| CN-101212899-B | Carboxamides | BAYER CROPSCIENCE AG | 2012-11-21 | — | — | CN | disclosed |
| US-7897780-B2 | Method for controlling phytopathogenic fungi using silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2011-03-01 | — | — | US | disclosed |
| US-20090105311-A1 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105311-A1 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-1890540-A2 | CARBOXAMIDES | Bayer CropScience AG (DE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070293455-A1 | Silylated Carboxamides | BAYER CROPSCIENCE AG (DE) | 2007-12-20 | — | — | US | disclosed |
| WO-2006131221-A2 | CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293455-A1 | Silylated Carboxamides | MRPL21, MRPS22, MRM1 | RAB9A 2076/4885SMN1; SMN2 1838/4885NPC1 3441/4885 |
| US-20090105311-A1 | Carboxamides | NAAA, CBR3, CNR1 | RAB9A 2505/4885SMN1; SMN2 2586/4885NPC1 3367/4885 |
| US-20130190375-A1 | CARBOXAMIDES | NAAA, CBR3, CNR1 | RAB9A 2505/4885SMN1; SMN2 2586/4885NPC1 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.