Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 5/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645337 | 1.00 | TGFBR1 (0.37) | TGFBR1THRBMAPK14AOC3CCNE1 | |
| SCHEMBL23652810 | 0.85 | TGFBR1 (0.39) | TGFBR1THRBMAPK14ACVR1GRM5 | |
| SCHEMBL20213765 | 0.76 | PTPN1 (0.40) | ACVR1 | |
| SCHEMBL21315407 | 0.73 | KCNK3 (0.33) | KCNK3 | |
| SCHEMBL23645307 | 0.66 | POLB (0.31) | — | |
| SCHEMBL23652637 | 0.66 | — | — | |
| SCHEMBL24581298 | 0.63 | ECE1 (0.54) | — | |
| SCHEMBL12359155 | 0.62 | IRAK4 (0.49) | — | |
| SCHEMBL22767997 | 0.61 | KMT2A (0.43) | — | |
| SCHEMBL6200651 | 0.61 | RAB9A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689636-B | Novel heteroatom aromatic amide derivative and pharmaceutical agent containing same | 科研制药株式会社 | 2024-08-20 | — | — | CN | disclosed |