Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069447 | 0.83 | GRM2 (0.37) | KDM4ECYP1A2CYP3A4CYP2C19GRM2 | |
| SCHEMBL3734568 | 0.83 | GRM2 (0.46) | CYP3A4CYP2C19GRM2STING1L3MBTL1 | |
| SCHEMBL7879921 | 0.78 | GNRHR (0.43) | CYP3A4CYP2C19GRM2STING1L3MBTL1 | |
| SCHEMBL31069448 | 0.76 | CNR2 (0.35) | KDM4ECNR2MEN1KMT2AGAA | |
| SCHEMBL6245220 | 0.72 | GRM2 (0.47) | CYP3A4CYP2C19GRM2CNR2STING1 | |
| SCHEMBL23928856 | 0.72 | CHRNA7 (0.57) | KDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30587447 | 0.72 | CHRNA7 (0.57) | KDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29269258 | 0.70 | CACNA1H (0.50) | KDM4ECYP1A2CYP3A4CYP2C19GRM2 | |
| SCHEMBL3737024 | 0.69 | GNRHR (0.48) | CYP3A4CYP2C19CNR2STING1BRD4 | |
| SCHEMBL31069435 | 0.69 | GRM2 (0.47) | KDM4ECYP1A2CYP3A4CYP2C19GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174953-A1 | BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2024-08-29 | — | — | WO | disclosed |