Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 18/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928856 | 1.00 | CHRNA7 (0.57) | CHRNA7TRPV1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8047542 | 0.85 | BRD4 (0.44) | CHRNA7KDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL23928858 | 0.81 | CHRNA7 (0.64) | CHRNA7TRPV1KDM4E | |
| SCHEMBL13837417 | 0.80 | BRD9 (0.47) | KDM4E | |
| SCHEMBL17653861 | 0.80 | CACNA1H (0.46) | CHRNA7 | |
| SCHEMBL29269258 | 0.80 | CACNA1H (0.50) | TRPV1KDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31035896 | 0.79 | CHRNA7 (0.58) | CHRNA7TRPV1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL10165151 | 0.78 | POLB (0.52) | KDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20946419 | 0.78 | GAA (0.46) | KDM4E | |
| SCHEMBL3180689 | 0.77 | L3MBTL1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820869-B1 | SPIROCHROMANE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2023-08-30 | — | — | EP | disclosed |