Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069468 | 1.00 | POLB (0.42) | POLBPTGER4KDM4EALDH1A1GAA | |
| SCHEMBL3061472 | 0.86 | ALOX5AP (0.43) | PTGER4KDM4EALDH1A1GAAGLA | |
| SCHEMBL3731009 | 0.86 | CNR2 (0.47) | ALOX5APMAPK1 | |
| Hydrochloric Acid SCHEMBL3063212 | 0.85 | ALOX5AP (0.42) | PTGER4KDM4EALDH1A1GAAGLA | |
| SCHEMBL3729573 | 0.81 | RAB9A (0.42) | POLBKDM4EALDH1A1GAAGLA | |
| SCHEMBL1206745 | 0.79 | HDAC1 (0.41) | PTGER4 | |
| SCHEMBL6489644 | 0.78 | SMN1; SMN2 (0.43) | PTGER4ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL31069471 | 0.77 | POLB (0.46) | POLBKDM4ELMNAKMT2AJAK2 | |
| SCHEMBL13077881 | 0.76 | TSHR (0.61) | S1PR1ALOX5APMAPK1 | |
| SCHEMBL7019632 | 0.76 | CYP11B2 (0.47) | POLBSMN1; SMN2RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174953-A1 | BENZIMIDAZOLE DERIVATIVE AND MEDICAL USE THEREOF | 苏州隆博泰药业有限公司 | 2024-08-29 | — | — | WO | disclosed |