Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 4/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10978751 | 1.00 | GPR3 (0.42) | GPR3MPOPDE2AADRB2FFAR4 | |
| SCHEMBL30553357 | 0.85 | PDE2A (0.44) | GPR3PDE2AFFAR4FFAR1TRPV1 | |
| SCHEMBL23780516 | 0.85 | PDE2A (0.44) | GPR3PDE2AFFAR4FFAR1TRPV1 | |
| SCHEMBL4550397 | 0.81 | MPO (0.44) | GPR3MPOPDE2AADRB2FFAR4 | |
| SCHEMBL20590929 | 0.81 | GPR3 (0.42) | GPR3MPOPDE2AADRB2FFAR4 | |
| SCHEMBL15599254 | 0.81 | PDE2A (0.44) | GPR3MPOPDE2AADRB2FFAR4 | |
| SCHEMBL10977660 | 0.81 | GPR3 (0.42) | GPR3MPOPDE2AADRB2FFAR4 | |
| SCHEMBL11030156 | 0.81 | FFAR4 (0.49) | GPR3MPOADRB2FFAR4ALKBH1 | |
| SCHEMBL2291338 | 0.81 | GPR3 (0.42) | GPR3PDE2AKIF11 | |
| SCHEMBL29786515 | 0.81 | MPO (0.44) | GPR3MPOPDE2AADRB2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739669-A1 | SODIUM CHANNEL BLOCKERS | Novartis AG (CH) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025011450-A1 | SODIUM CHANNEL BLOCKERS | NOVARTIS AG (CH) | 2025-01-16 | — | — | WO | disclosed |
| CN-118556044-A | Fused heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-08-27 | — | — | CN | disclosed |