Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069750 | 1.00 | HPGD (0.58) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL24851242 | 0.90 | RAB9A (0.69) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL12331161 | 0.83 | ALDH1A1 (0.53) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL67641 | 0.83 | ALDH1A1 (0.53) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL27437689 | 0.83 | ALDH1A1 (0.53) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL67640 | 0.83 | ALDH1A1 (0.53) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL23646041 | 0.82 | ALDH1A1 (0.43) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL2326261 | 0.81 | ALDH1A1 (0.65) | HPGDRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL59844 | 0.78 | ALDH1A1 (0.69) | HPGDKMT2AMEN1ALDH1A1GFER | |
| SCHEMBL28027772 | 0.78 | RAB9A (0.55) | HPGDRAB9AKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118593448-A | Tumor specific therapeutic diagnostic nano-agent and preparation method and application thereof | 南开大学 | 2024-09-06 | — | — | CN | disclosed |