SCHEMBL67640

SCHEMBL67640

Brc1ccc(/C(=C(\c2ccccc2)c2ccc(Br)cc2)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
MAPK1 P28482 1/20 0.50
AKR1C3 P42330 1/20 0.48
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
TP53 P04637 1/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
MAPT P10636 1/20 0.46
CYP1B1 Q16678 1/20 0.45
CYP2A6 P11509 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
NFKB1 P19838 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27437689 1.00 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1AKR1C3CES2
SCHEMBL12331161 1.00 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1AKR1C3CES2
SCHEMBL67641 1.00 ALDH1A1 (0.53) ALDH1A1TDP1MAPK1AKR1C3CES2
SCHEMBL29244386 0.91 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1AKR1C3MEN1
SCHEMBL19859195 0.91 ALOX15 (0.59) ALDH1A1TDP1CES2MEN1KMT2A
SCHEMBL29244385 0.91 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1AKR1C3MEN1
SCHEMBL19859420 0.91 ALOX15 (0.59) ALDH1A1TDP1CES2MEN1KMT2A
SCHEMBL19859193 0.91 ALOX15 (0.59) ALDH1A1TDP1CES2MEN1KMT2A
SCHEMBL28548057 0.89 ALDH1A1 (0.56) ALDH1A1TDP1MAPK1AKR1C3CES2
SCHEMBL17202274 0.88 CES2 (0.58) ALDH1A1MAPK1CES2CES1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391800-B1 Tetraphenylethene-based polymers for supercapacitors IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-08-19 US disclosed
CN-118459508-A Iridium complex for inducing Mutp to degrade and preparation method and application thereof 南京师范大学 2024-08-09 CN disclosed
CN-118005601-A Compound with aggregation-induced emission performance and preparation method thereof 五邑大学 2024-05-10 CN disclosed
EP-3601407-B1 FLUORESCENT POROUS ORGANIC NANOSHEETS FOR CHEMICAL SENSING NAT UNIV SINGAPORE (SG) 2023-10-25 EP disclosed
US-11447606-B2 Fluorescent porous organic nanosheets for chemical sensing NATIONAL UNIVERSITY OF SINGAPORE (SG) 2022-09-20 US disclosed
WO-2020043087-A1 METHOD OF DETECTING HUMAN SERUM ALBUMIN IN BIOLOGICAL FLUIDS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2020-03-05 WO disclosed
WO-2018108070-A1 LUMINOGENS FOR BIOLOGICAL APPLICATIONS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-06-21 WO disclosed
US-9518921-B2 Silica nanoparticles with aggregation induced emission characteristics as fluorescent bioprobe for intracellular imaging and protein carrier THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) 2016-12-13 US disclosed
US-9279806-B2 Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-03-08 US disclosed
US-9279806-B2 Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-03-08 US disclosed
US-8129111-B2 Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2012-03-06 US disclosed
US-7939613-B2 Probes/sensors for biomacromolecules; films; cosmetics THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2011-05-10 US disclosed
US-7939613-B2 Probes/sensors for biomacromolecules; films; cosmetics THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2011-05-10 US disclosed
US-7939613-B2 Probes/sensors for biomacromolecules; films; cosmetics THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2011-05-10 US disclosed
US-20100009362-A1 Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2010-01-14 US disclosed
US-20100009362-A1 Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2010-01-14 US disclosed
US-20080220407-A1 Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2008-09-11 US disclosed
US-20080220407-A1 Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2008-09-11 US disclosed
US-20080220407-A1 Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2008-09-11 US disclosed
US-6340732-B1 FORMING PHOTOLUMINESCENT OR ELECTROLUMINESCENT POLYARYLENE VINYLENE POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2002-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080220407-A1 Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same FUS, CD63, EPCAM ALDH1A1 1173/4885TDP1 300/4885MAPK1 4368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.