Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27876353 | 0.91 | L3MBTL1 (0.42) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL1536109 | 0.90 | L3MBTL1 (0.42) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL14794936 | 0.86 | L3MBTL1 (0.39) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL1933800 | 0.86 | L3MBTL1 (0.39) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL13580580 | 0.82 | HSD11B1 (0.37) | L3MBTL1HTTMETKMT2AMEN1 | |
| SCHEMBL1535993 | 0.81 | HSD11B1 (0.37) | L3MBTL1POLBHTTMETKMT2A | |
| SCHEMBL4350480 | 0.81 | ALDH1A1 (0.37) | L3MBTL1POLBKMT2AMEN1F2 | |
| SCHEMBL2318675 | 0.80 | L3MBTL1 (0.47) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL1536091 | 0.80 | L3MBTL1 (0.43) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL30007018 | 0.80 | L3MBTL1 (0.43) | L3MBTL1POLBHTTALDH3A1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598876-A | Preparation method of 5-toluenesulfonyl-5H-pyrrolo [2,3-b ] pyrazine-2-amine hydrochloride | 南方科技大学坪山生物医药研究院 | 2024-09-06 | — | — | CN | disclosed |