Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12231213 | 0.86 | MAPT (0.60) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL21668583 | 0.84 | MAPT (0.74) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL701961 | 0.84 | MAPT (1.00) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL29633530 | 0.84 | MAPT (1.00) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL481193 | 0.84 | MAPT (0.53) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL27705271 | 0.84 | MAPT (0.53) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1559781 | 0.83 | MAPT (0.72) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL10245317 | 0.82 | MAPT (0.51) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL9123233 | 0.82 | MAPT (0.71) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL9909661 | 0.81 | L3MBTL1 (0.69) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515682-A | Dolichosin A preparation method and intermediate thereof | 成都科岭源医药技术有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-118515638-A | Dolichosin A and preparation method of intermediate thereof | 成都科岭源医药技术有限公司 | 2024-08-20 | — | — | CN | disclosed |