Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069940 | 0.86 | KDM4E (0.52) | CA2L3MBTL1MMP2KDM4ELMNA | |
| SCHEMBL10658071 | 0.83 | CA2 (0.58) | CA2TDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL10658082 | 0.83 | CA2 (0.58) | CA2TDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL11084329 | 0.81 | CA2 (0.47) | CA2MMP2KDM4ELMNAGLA | |
| SCHEMBL11122413 | 0.81 | CA2 (0.62) | CA2KDM4ELMNAGLAMAPT | |
| SCHEMBL25249160 | 0.80 | CA2 (1.00) | CA2TDP1L3MBTL1ALDH1A1CA1 | |
| SCHEMBL16369616 | 0.80 | CA2 (1.00) | CA2TDP1L3MBTL1ALDH1A1CA1 | |
| SCHEMBL16369614 | 0.80 | CA2 (1.00) | CA2TDP1L3MBTL1ALDH1A1CA1 | |
| SCHEMBL11084531 | 0.79 | CA2 (0.44) | CA2KDM4ELMNAGLAMAPT | |
| SCHEMBL11084537 | 0.79 | CA2 (0.44) | CA2KDM4ELMNAGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684654-A | Compound with antihypertensive activity and synthesis method thereof | 复旦大学 | 2024-09-24 | — | — | CN | disclosed |