Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31070035 | 0.84 | MAPT (0.50) | NPC1MAPTRAB9AHSD17B1MCHR1 | |
| SCHEMBL11679201 | 0.66 | RAB9A (0.51) | NPC1MAPTRAB9AHSD17B1SRD5A2 | |
| SCHEMBL11679519 | 0.64 | MAPT (0.49) | NPC1MAPTRAB9AHSD17B1MCHR1 | |
| Hydrochloric Acid SCHEMBL11678026 | 0.64 | MAPT (0.56) | NPC1MAPTRAB9AHSD17B1MCHR1 | |
| SCHEMBL11678574 | 0.64 | KDM4E (0.54) | NPC1MAPTRAB9AMCHR1KDM4E | |
| SCHEMBL6724547 | 0.63 | TSHR (0.55) | NPC1MAPTKDM4EL3MBTL1PGR | |
| Hydrochloric Acid SCHEMBL31070038 | 0.63 | PDPK1 (0.49) | KDM4EHTR7HTR2BKMT2A | |
| SCHEMBL11780746 | 0.62 | NPC1 (0.53) | NPC1MAPTRAB9AHSD17B1SRD5A2 | |
| SCHEMBL11677514 | 0.62 | MAPT (0.53) | NPC1MAPTRAB9AHSD17B1MCHR1 | |
| SCHEMBL11678405 | 0.61 | NPC1 (0.51) | NPC1MAPTRAB9AHSD17B1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111514123-B | Use of teloxone analogues for combating viral infections | 江苏伯克生物医药股份有限公司 | 2024-09-10 | — | — | CN | disclosed |