Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863346 | 0.84 | OPRK1 (0.36) | MAPTRAB9ANPC1KDM4EDRD2 | |
| SCHEMBL11797647 | 0.84 | HPGD (0.41) | KDM4ECTNNB1WNT3ACYP3A4ALDH1A1 | |
| SCHEMBL11753618 | 0.78 | KDM4E (0.36) | MAPTRAB9ANPC1HSD17B1KDM4E | |
| SCHEMBL11679519 | 0.78 | MAPT (0.49) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11679975 | 0.77 | KDM4E (0.52) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11679201 | 0.77 | RAB9A (0.51) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11679626 | 0.76 | MAPT (0.58) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL2938985 | 0.76 | RAB9A (0.58) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11677470 | 0.76 | RAB9A (0.53) | MAPTRAB9ANPC1HSD17B1SRD5A2 | |
| SCHEMBL11677849 | 0.76 | L3MBTL1 (0.56) | MAPTRAB9ANPC1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |