Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677849 | 0.89 | L3MBTL1 (0.56) | KDM4EL3MBTL1CHRM2ADRA2BDRD3 | |
| SCHEMBL11675968 | 0.88 | L3MBTL1 (0.58) | KDM4EL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL11678584 | 0.79 | KDM4E (0.62) | KDM4EL3MBTL1HRH3MAPTNPC1 | |
| SCHEMBL11679201 | 0.78 | RAB9A (0.51) | KDM4EL3MBTL1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11678840 | 0.78 | ALPL (0.64) | KDM4EL3MBTL1HRH3MAPTNPC1 | |
| SCHEMBL11678598 | 0.78 | L3MBTL1 (0.72) | KDM4EL3MBTL1CHRM2HRH3MAPT | |
| Hydrochloric Acid SCHEMBL11679014 | 0.77 | L3MBTL1 (0.70) | KDM4EL3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL11679519 | 0.76 | MAPT (0.49) | KDM4EL3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL11679191 | 0.76 | KDM4E (0.81) | KDM4EL3MBTL1DRD3HRH3MAPT | |
| SCHEMBL11679975 | 0.75 | KDM4E (0.52) | KDM4EL3MBTL1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |