Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12649229 | 0.69 | DRD2 (0.50) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL31444391 | 0.68 | CHRNB2 (0.44) | SLC6A3CHRNB2CHRNA4SMN1; SMN2PNMT | |
| Hydrochloric Acid SCHEMBL1769107 | 0.68 | DRD2 (0.49) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL31070455 | 0.68 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL6985456 | 0.67 | PRCP (0.66) | DRD2SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL7705422 | 0.67 | SMN1; SMN2 (0.44) | SLC6A4SLC6A2SLC6A3SMN1; SMN2ALDH1A1 | |
| SCHEMBL13584551 | 0.67 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL31070628 | 0.67 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL4306669 | 0.66 | SLC6A2 (1.00) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL5345151 | 0.66 | DRD1 (0.40) | CHRNB2CHRNA4DRD2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |