Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070636 | 0.93 | IDO1 (0.34) | MAP2IDO1TRPV1HSD11B1SLC6A2 | |
| SCHEMBL31083745 | 0.92 | MAP2 (0.36) | MAP2IDO1KLKB1MAP4K1MRGPRX4 | |
| SCHEMBL31070569 | 0.86 | HSD11B1 (0.44) | IDO1HSD11B1SLC6A4HTR1AHTR2A | |
| SCHEMBL31070496 | 0.86 | KIF11 (0.40) | MAP2IDO1HTR1AHTR2AHTR7 | |
| SCHEMBL31083718 | 0.84 | TRPV1 (0.36) | MAP2IDO1TRPV1HSD11B1SLC6A4 | |
| SCHEMBL31070505 | 0.83 | POLB (0.39) | TRPV1 | |
| SCHEMBL31070444 | 0.83 | IDO1 (0.39) | MAP2IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31070656 | 0.82 | KDM4E (0.39) | TRPV1HSD11B1 | |
| SCHEMBL31070481 | 0.82 | MAP2 (0.41) | MAP2IDO1 | |
| SCHEMBL31083692 | 0.78 | HSD11B1 (0.43) | HSD11B1SLC6A4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |