Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070505 | 0.99 | POLB (0.39) | KDM4EPOLBBRD4ALDH1A1CREBBP | |
| SCHEMBL30593210 | 0.90 | KIF11 (0.42) | KDM4EPOLBBRD4ALDH1A1CREBBP | |
| SCHEMBL31070496 | 0.86 | KIF11 (0.40) | KIF11MAPT | |
| SCHEMBL31070569 | 0.86 | HSD11B1 (0.44) | ALDH1A1HSD11B1 | |
| SCHEMBL31070636 | 0.85 | IDO1 (0.34) | MAPTHSD11B1TRPV1ADRA1D | |
| SCHEMBL31070542 | 0.82 | KCNA3 (0.46) | KDM4EPOLBBRD4ALDH1A1CREBBP | |
| SCHEMBL31070623 | 0.82 | ECE1 (0.40) | KDM4EPOLBBRD4ALDH1A1CREBBP | |
| SCHEMBL31070485 | 0.82 | MAP2 (0.37) | HSD11B1TRPV1 | |
| SCHEMBL30593208 | 0.82 | KIF11 (0.44) | KDM4EPOLBBRD4ALDH1A1CREBBP | |
| SCHEMBL31070532 | 0.80 | CCR2 (0.44) | KDM4EPOLBBRD4ALDH1A1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |