Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070558 | 0.93 | IDO1 (0.34) | RORCIDO1CCR2KIF11 | |
| SCHEMBL31083729 | 0.91 | NTRK1 (0.34) | RORCIDO1CCR2NTRK1FLT3 | |
| SCHEMBL31070564 | 0.84 | IDO1 (0.35) | IDO1KIF11TDO2 | |
| SCHEMBL31070454 | 0.81 | PRKAB2 (0.43) | IDO1 | |
| SCHEMBL31070447 | 0.80 | PRKAB2 (0.38) | — | |
| SCHEMBL31070641 | 0.78 | IDO1 (0.39) | IDO1CCR2KIF11TDO2 | |
| SCHEMBL31070481 | 0.78 | MAP2 (0.41) | RORCIDO1KIF11 | |
| SCHEMBL30593229 | 0.75 | ESR1 (0.39) | IDO1KIF11SCN9A | |
| SCHEMBL31070636 | 0.75 | IDO1 (0.34) | IDO1 | |
| SCHEMBL31070544 | 0.74 | ICMT (0.43) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |