Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | MAP2 | P11137 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070486 | 0.93 | RORC (0.34) | IDO1RORCCCR2KIF11 | |
| SCHEMBL31070481 | 0.85 | MAP2 (0.41) | IDO1ICMTRORCMAP2PRKAB2 | |
| SCHEMBL31083729 | 0.85 | NTRK1 (0.34) | IDO1RORCCCR2KIF11 | |
| SCHEMBL31070565 | 0.82 | PRKAB2 (0.41) | IDO1ICMTMAP2PRKAB2PRKAG1 | |
| SCHEMBL31070609 | 0.81 | PRKAB2 (0.42) | ICMTMAP2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL31070444 | 0.80 | IDO1 (0.39) | IDO1ICMTMAP2KIF11 | |
| SCHEMBL31070564 | 0.78 | IDO1 (0.35) | IDO1ICMTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL31070485 | 0.77 | MAP2 (0.37) | IDO1MAP2 | |
| SCHEMBL30593278 | 0.77 | MAP2 (0.40) | IDO1ICMTRORCMAP2PRKAB2 | |
| SCHEMBL29084778 | 0.77 | MAP2 (0.40) | IDO1ICMTRORCMAP2PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515600-A | Isoindoline compound and medical application thereof | 中国科学院上海药物研究所 | 2024-08-20 | — | — | CN | disclosed |